Diffractive paths for weak localization in quantum billiards

We study the weak localization effect in quantum transport through a clean ballistic cavity with regular classical dynamics. We address the question which paths account for the suppression of conductance through a system where disorder and chaos are absent. By exploiting both quantum and semiclassical methods, we unambiguously identify paths that are diffractively backscattered into the cavity (when approaching the lead mouths from the cavity interior) to play a key role. Diffractive scattering couples transmitted and reflected paths and is thus essential to reproduce the weak-localization peak in reflection and the corresponding anti-peak in transmission. A comparison of semiclassical calculations featuring these diffractive paths yields good agreement with full quantum calculations and experimental data. Our theory provides system-specific predictions for the quantum regime of few open lead modes and can be expected to be relevant also for mixed as well as chaotic systems.Comment: 5 pages, 3 figures, final version with extended discussion and added reference

Inhaled iloprost for the control of pulmonary hypertension

Pulmonary arterial hypertension (PAH) is a life-threatening disease characterized by an elevated pulmonary arterial pressure and vascular resistance with a poor prognosis. Various pulmonary and extrapulmonary causes are now recognized to exist separately from the idiopathic form of pulmonary hypertension. An imbalance in the presence of vasoconstrictors and vasodilators plays an important role in the pathophysiology of the disease, one example being the lack of prostacyclin. Prostacyclin and its analogues are potent vasodilators with antithrombotic, antiproliferative and anti-inflammatory qualities, all of which are important factors in the pathogenesis of precapillary pulmonary hypertension. Iloprost is a stable prostacyclin analogue available for intravenous and aerosolized application. Due to the severe side effects of intravenous administration, the use of inhaled iloprost has become a mainstay in PAH therapy. However, owing to the necessity for 6 to 9 inhalations a day, oral treatment is often preferred as a first-line therapy. Numerous studies proving the efficacy and safety of inhaled iloprost have been performed. It is therefore available for a first-line therapy for PAH. The combination with endothelin-receptor antagonists or sildenafil has shown encouraging effects. Further studies with larger patient populations will have to demonstrate the use of combination therapy for long-term treatment of pulmonary hypertension

Application Migration Effort in the Cloud

Over the last years, the utilization of cloud resources has been steadily rising and an increasing number of enterprises are moving applications to the cloud. A leading trend is the adoption of Platform as a Service to support rapid application deployment. By providing a managed environment, cloud platforms take away a lot of complex configuration effort required to build scalable applications. However, application migrations to and between clouds cost development effort and open up new risks of vendor lock-in. This is problematic because frequent migrations may be necessary in the dynamic and fast changing cloud market. So far, the effort of application migration in PaaS environments and typical issues experienced in this task are hardly understood. To improve this situation, we present a cloud-to-cloud migration of a real-world application to seven representative cloud platforms. In this case study, we analyze the feasibility of the migrations in terms of portability and the effort of the migrations. We present a Docker-based deployment system that provides the ability of isolated and reproducible measurements of deployments to platform vendors, thus enabling the comparison of platforms for a particular application. Using this system, the study identifies key problems during migrations and quantifies these differences by distinctive metrics

Минерально-геохимические особенности крови человека как индикатор условий его проживания на территориях с различной экологической ситуацией

В работе показано содержание научного доклада по теме диссертационной работы на тему "Минерально-геохимические особенности крови человека как индикатор условий его проживания на территориях с различной экологической ситуацией". Представлены материалы, методы и результаты исследования комплекса компонентов природной среды на территории, прилегающей к зоне Семипалатинского испытательного ядерного полигона.The paper shows the content of the scientific report on the theme of the thesis "Mineral-geochemical features of human blood as an indicator of the conditions of his residence in areas with different environmental situation." The presented materials, methods and results of research of a complex of components of the natural environment in the territory adjacent to the zone of the Semipalatinsk nuclear test site